Personally I find it so much easier playing end on, (the game isnt hard no matter what you do really) but if im playing online im swapping straight to end on because the advantage feels massive in Rugby 25.
Seems to be a common reason people play end on because thats how it is in real life. But it isnt really. its certainly closer, you run in the direction you would run if you are on the pitch (my brain cant handle the spinning camera on posession swap), but for me theres still a huge advantage to just being able to have this view of the entire pitch as you are playing which isnt how it is IRL, you can just pick running lines and kicks exactly where you want, and can even change your decisions on the fly because you just avoid the backfield AI, rather than attempting the tactical kick, where maybe the AI is able to cover and sweep it up. If I play on end camera I feel like I can just batter the AI in to submission, Ive had games were im finishing with >95% territory becuase you can just kick to grass for fun. Along with the shift in button layout to just be “push forward” makes other things so easy. hitting a drop goal is basically unmissable on end on, hitting a line break is so easy because the gap is right there and you can see where the fullback is for cover, and choose where you want to break though.
Having played with people on the discord and done my own testing, it feels like the more extreme the camera angle is the easier the game plays.
Most people playing on end on probably play with a camera like this:
But i saw people playing with cameras like this:
And I messed about with it myself and having this super high up end on camera gives you so much visual info 100% of the time, the game feels much easier, for online multiplayer especially it feels to me like theres a meta to it, becuase I can put a kick anywhere in to space away from my opponents players and they cant do anything about it.
Whereas on the side camera, you dont have that info available all the time, even on the max FOV im still not sure if they have this bottom right side of the field covered, so for me thats what adds a level of difficulty, and risk. But on top of that, the controls being rotated also make gauging that kick placement tougher too. So takes some getting used to, muscle memory and a bit of skill, especially with drop goals. Not “hard” once you get used to it, but certainly harder than on end on.
For me if you wanted to play rugby as close to IRL as possible, then really the camera settings should allow you to play like this:
Which honestly, I think might be really fun to try, actually playing from a players height, you get the closest level of realism, you can still pick some good running lines, you can still see the space in the back field, BUT judging the kicks into that space would require a good amound of skill to land correctly.
But I doubt many people would want to play like that, because the difficulty of getting closer to IRL would be too much for a lot of people, but might be a fun challenge mode or something. One thing I brought up with JNT a long time ago was asking if the space on the field changes depending on camera mode? Logically it makes no sense, but it felt true from a linebreak standpoint, so there must be other factors at play.
So is the space in red in images below the same amount of tangable space to run through?
And the answer from JNT was yes, it has be the same which is what I expected. However, if i do a one off runner on end on camera, i reckon theres a 70% my guy gets through those 2 players untouched. Whereas on side camera, I reckon it drops to maybe 10-20%. And im not sure why, maybe the controls rotating make it slightly trickier for your thumbs to pick a straight line, maybe the AI on side camera move latterally quicker, maybe the AI tackle radius doesnt account for the side camera and therefor they can tackle further away? But I even tested for it a number of updates ago. And was litterally swapping the camera from phase to phase, just doing 1 off runners hitting the gap. And the success rate on end on is so much higher. Havnt tested that in maybe a good 10 updates or so, so may well have changed wit the updates to the AI’s defence.
Even the CEO at BigAnt said he doesnt play Side on because its too hard 
I dont mind how people play, its a video game, best to enjoy it however resonates with you. But there are a number of issues that I do seem to stumble into on side camera, whereas end on is just a challengless breeze.
Feel like ive looked in to camera orientations impacts on the game more than bigant ant this point, hopefully Rugby 27 somes with a VR headset and you see through the players eyes, and I never have to think about cameras again.
EDIT
Decided to have a game using the match I was grabbing screenshots on just as a challenge of how easy kicking is on End On. So rules are, cant run forwards with the ball, cant use hand off, cant use grubber kicks / chip kicks / up and unders, must kick long to space to move up the field, cant score tries or penalites only drop goals.
Deduct about 5 mins of the overall match because I was grabbing the screenshots for the post. But in 75 minutes of a 5 minute match on hardest, I won 24-0 by landing 8/8 goals. 73% posession and 62% territory (if you believe the stats which im not sure if any of them are calculated 100% right), without carrying the ball forwards. Just utilising the end on camera to kick to space repeatedly, then knocking over a drop goal. And the AI couldnt do anything to stop me. (doesnt help the AI is also terrible, and the also random team I had was Fiji who are 85 compared to France’s 88 rating) but its just so easy to not even interact with the game properly and just win with kicks.
, a quick update on important gameplay fixes. 
-Nerfs, the noise, they’re too strong, it’s unrealistic.
I guess.